E-Numbers to Avoid — Additives With Real Concerns

Most E-numbers are harmless — but not all. This guide lists the 5 additives that are banned or heavily restricted somewhere in the world, plus the 79 where genuine concerns or conditions apply, from hyperactivity warnings to allergen rules.

A note on perspective: an E-number is only granted after an EFSA safety assessment, and the additives below are still legal in at least some markets. 'Avoid' here means credible, documented concerns exist — regulatory bans elsewhere, mandatory warning labels, allergen status, or EFSA findings that intake exceeds safe levels for some groups. It doesn't mean a single biscuit will harm you.

Banned or restricted somewhere

Banned in at least one major market, or restricted to very narrow uses.

E-NumberNameSafetyDetails
E123 Amaranth Banned/Restricted Full details
E171 Titanium Dioxide Banned/Restricted Full details
E952 Cyclamate Banned/Restricted Full details
E284 Boric Acid Avoid Full details
E285 Sodium Tetraborate Avoid Full details

Approved but with concerns

Legal and widespread, but carrying warning labels, allergen rules or active scientific debate.

E-NumberNameSafetyDetails
E102 Tartrazine Some Concerns Full details
E104 Quinoline Yellow Some Concerns Full details
E110 Sunset Yellow FCF Some Concerns Full details
E120 Carmine Some Concerns Full details
E122 Carmoisine Some Concerns Full details
E124 Ponceau 4R Some Concerns Full details
E127 Erythrosine Some Concerns Full details
E129 Allura Red AC Some Concerns Full details
E131 Patent Blue V Some Concerns Full details
E142 Green S Some Concerns Full details
E151 Brilliant Black BN Some Concerns Full details
E155 Brown HT Some Concerns Full details
E173 Aluminium Some Concerns Full details
E174 Silver Some Concerns Full details
E175 Gold Some Concerns Full details
E180 Litholrubine BK Some Concerns Full details
E210 Benzoic Acid Some Concerns Full details
E211 Sodium Benzoate Some Concerns Full details
E212 Potassium Benzoate Some Concerns Full details
E213 Calcium Benzoate Some Concerns Full details
E214 Ethyl para-hydroxybenzoate Some Concerns Full details
E215 Sodium ethyl para-hydroxybenzoate Some Concerns Full details
E218 Methyl para-hydroxybenzoate Some Concerns Full details
E219 Sodium methyl para-hydroxybenzoate Some Concerns Full details
E220 Sulphur Dioxide Some Concerns Full details
E221 Sodium Sulphite Some Concerns Full details
E222 Sodium Bisulphite Some Concerns Full details
E223 Sodium Metabisulphite Some Concerns Full details
E224 Potassium Metabisulphite Some Concerns Full details
E226 Calcium Sulphite Some Concerns Full details
E227 Calcium Bisulphite Some Concerns Full details
E228 Potassium Bisulphite Some Concerns Full details
E239 Hexamethylene Tetramine Some Concerns Full details
E249 Potassium Nitrite Some Concerns Full details
E250 Sodium Nitrite Some Concerns Full details
E251 Sodium Nitrate Some Concerns Full details
E252 Potassium Nitrate Some Concerns Full details
E310 Propyl Gallate Some Concerns Full details
E311 Octyl Gallate Some Concerns Full details
E312 Dodecyl Gallate Some Concerns Full details
E319 TBHQ Some Concerns Full details
E320 BHA Some Concerns Full details
E321 BHT Some Concerns Full details
E338 Phosphoric Acid Some Concerns Full details
E339 Sodium Phosphates Some Concerns Full details
E340 Potassium Phosphates Some Concerns Full details
E341 Calcium Phosphates Some Concerns Full details
E385 Calcium Disodium EDTA Some Concerns Full details
E407 Carrageenan Some Concerns Full details
E432 Polysorbate 20 Some Concerns Full details
E433 Polysorbate 80 Some Concerns Full details
E434 Polysorbate 40 Some Concerns Full details
E435 Polysorbate 60 Some Concerns Full details
E436 Polysorbate 65 Some Concerns Full details
E450 Diphosphates Some Concerns Full details
E451 Triphosphates Some Concerns Full details
E452 Polyphosphates Some Concerns Full details
E466 Carboxymethyl Cellulose Some Concerns Full details
E471 Mono- and Diglycerides of Fatty Acids Some Concerns Full details
E512 Stannous Chloride Some Concerns Full details
E520 Aluminium Sulphate Some Concerns Full details
E521 Aluminium Sodium Sulphate Some Concerns Full details
E522 Aluminium Potassium Sulphate Some Concerns Full details
E523 Aluminium Ammonium Sulphate Some Concerns Full details
E541 Sodium Aluminium Phosphate Some Concerns Full details
E542 Bone Phosphate Some Concerns Full details
E554 Sodium Aluminium Silicate Some Concerns Full details
E555 Potassium Aluminium Silicate Some Concerns Full details
E556 Calcium Aluminium Silicate Some Concerns Full details
E950 Acesulfame K Some Concerns Full details
E951 Aspartame Some Concerns Full details
E954 Saccharin Some Concerns Full details
E955 Sucralose Some Concerns Full details
E962 Salt of Aspartame-Acesulfame Some Concerns Full details
E150c Ammonia Caramel Some Concerns Full details
E150d Sulphite Ammonia Caramel Some Concerns Full details
E161g Canthaxanthin Some Concerns Full details
E407a Processed Eucheuma Seaweed Some Concerns Full details
E553b Talc Some Concerns Full details

For the additives banned outright somewhere in the world — and why regulators disagree — see our banned E-numbers guide. Parents may also want the E-numbers and ADHD guide covering the Southampton Six.

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Additive data sourced from Open Food Facts (ODbL licence) and the European Food Safety Authority (EFSA). This page is for general information and does not provide medical or dietary advice.

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